C4(alpha chain) antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d. Immunogen: complement component 4A(Rodgers blood group) Synonyms: Observed MW: 95 kDa Uniprot ID: P0C0L4 Reactivity: Human Tested Application: ELISA, WB, IHC Recommended dilution: WB: 1: 1000-1: 6000; IHC: 1: 50-1: 500 Gene ID: 720 Research Area: Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience